| IPAD-DB ID |
E00250 |
| Name |
Rhizophora mucronata Acetone extracts |
| Category |
Natural extracts |
| EC50 |
|
| IC50 |
259.56 ± 5.69 μg/ml(AChEI); 51.64 ± 0.24 μg/ml(Butyrylcholinesterase); |
| Inhibition |
100 μg/ml:34.97 ± 3.4%(AChEI); 97.27 ± 0.30%(Butyrylcholinesterase); 200 μg/ml:47.53 ± 4.52%(AChEI); 97.88 ± 0%(Butyrylcholinesterase); 300 μg/ml: 56.43 ± 5.42%(AChEI); 98.18 ± 0.30%(Butyrylcholinesterase); 400 μg/ml:62.25 ± 1.76%(AChEI); 98.02 ± 0.46%(Butyrylcholinesterase); 500 μg/ml: 62.32 ± 1.71%(AChEI); 98.48 ± 0.000013%(Butyrylcholinesterase); |
| Toxicity |
|
| ROS(reactive oxygen species) |
|
| Metal Chelating |
|
| BBB(blood-brain barrier) |
|
| Target Protein |
Acetylcholinesterase (AChE) |
| Effects |
(1) DPPH scavenging activity:48.34 ± 0.06% of inhibition; OH• scavenging activity: 85.54 ± 0.04% of inhibition; NO• scavenging activity: 84.58 ± 0.19% of inhibition; H2O2 scavenging activity: 83.46 ± 0.06% of inhibition; Metal chelating activity: 59.41 ± 0.01% of inhibition; |
| Research Models |
In vitro |
| Main Source |
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| Ref. Link |
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