Detailed Information for N00001
IPAD-DB ID N00001
Name 125I-CQ-PBCA NPs
Category Nano-inhibitors
EC50
IC50
Inhibition
Toxicity
ROS(reactive oxygen species)
Metal Chelating
BBB(blood-brain barrier) PASS
Target Protein Aβ1-42
Effects Have more efficient brain entry and rapid clearance in normal mice and enhance the retention in AD mouse brain demonstrating the ideal in vivo imaging characteristics; exhibit specificity for Aβ plaques both in vitro and in vivo
Research Models BALB/C and AD mice; in vitro
Main Source
Ref. Link