| IED ID |
IndEnz0002001995 |
| Enzyme Type ID |
protease001995 |
| Protein Name |
L-cystatin
|
| Gene Name |
|
| Organism |
Tachypleus tridentatus (Japanese horseshoe crab) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Ecdysozoa
Panarthropoda
Arthropoda
Chelicerata
Merostomata (horseshoe crabs)
Xiphosura
Limulidae
Tachypleus
Tachypleus tridentatus (Japanese horseshoe crab)
|
| Enzyme Sequence |
MEGYNILAVLIILVGVSMGQIPGGWIDANVGDTDVKEAARFATEAQSSRSNSLYHHKLLKIHKARTQVVSGINYEVFIETGTTTCKKSEVPLEDLKRCAVPENGVKHLCQAIVWVQAWIPRTKVTKLECQNKG |
| Enzyme Length |
133 |
| Uniprot Accession Number |
Q7M429 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Tight-binding inhibitor for papain. It has an important role in the protection of cells, antimicrobial activity against Gram-negative bacteria, defense against invading microbes, and response to external stimuli. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Disulfide bond (2); Modified residue (1); Motif (1); Signal peptide (1); Site (1) |
| Keywords |
Antibiotic;Antimicrobial;Direct protein sequencing;Disulfide bond;Protease inhibitor;Pyrrolidone carboxylic acid;Signal;Thiol protease inhibitor |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Cytoplasmic granule {ECO:0000269|PubMed:8907180}. Note=Large granules of hemocytes. |
| Modified Residue |
MOD_RES 20; /note=Pyrrolidone carboxylic acid; /evidence=ECO:0000255 |
| Post Translational Modification |
|
| Signal Peptide |
SIGNAL 1..19; /evidence=ECO:0000255 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
MOTIF 67..71; /note=Secondary area of contact; /evidence=ECO:0000250 |
| Gene Encoded By |
|
| Mass |
14,691 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
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